Emvólio: Revolutionizing Vaccine Cold Chain Management for India’s Health Sector

Emvólio: Revolutionizing Vaccine Cold Chain Management for India's Health Sector

In the face of significant vaccine wastage in India, Blackfrog Technologies, a Manipal-based startup, has developed Emvólio, a portable, battery-powered refrigeration unit. This innovation ensures vaccines are maintained at optimal temperatures, drastically reducing wastage and enhancing vaccine delivery efficiency. Emvólio has expanded its impact across 16 Indian states and into Africa.

Updated on: 19 June 2025

sector

Sector

Healthcare
education

Solution

Vaccine
Healthcare

Technology

Devices
space

State of Origin

Karnataka
Emvólio, a portable refrigeration unit developed by Blackfrog Technologies in India, revolutionizes vaccine storage by maintaining precise temperatures and reducing wastage up to 99%. Through innovative technology and strategic partnerships, Emvólio supports India's health missions, enhances public health logistics, and drives self-reliance in healthcare infrastructure. With proven success across states and borders, Emvólio emerges as a game-changer in vaccine logistics, paving the way for further advancements in health-tech innovation.

Impact Metrics

99% reduction

in vaccine wastage.

2-8°C

maintained for 12-20 hours.

Last-mile vaccine delivery

across 16 Indian states.

 

Vaccine wastage has long been a critical issue in India, with estimates indicating that 25% of vaccines are lost annually due to inadequate cold chain management. The COVID-19 pandemic highlighted this challenge, with some states reporting wastage rates as high as 37%. The root cause lies in the reliance on traditional iceboxes, which fail to maintain the necessary temperature range of 2℃ to 8℃, leading to spoilage and inefficacy of vaccines. This inefficiency not only wastes resources but also hampers the country’s immunization efforts, particularly in remote areas.

A Portable Breakthrough With Precision Cooling

Blackfrog Technologies, founded by Mayur Shetty in Manipal, Karnataka, has introduced Emvólio, a groundbreaking solution to this problem. Emvólio is a portable refrigeration unit that maintains vaccines at the required temperatures for up to 12 hours, with the potential to extend up to 20 hours. The device incorporates a patented rapid cooling technology, utilizing a Proportional Integral Derivative (PID) controller to ensure precise temperature control. This innovation eliminates the risks associated with traditional methods, such as accidental freezing or thawing, and significantly reduces maintenance costs due to its solid-state cooling mechanism.

Supporting India’s Health and Innovation Missions

Emvólio’s development and deployment reflect India’s broader commitment to strengthening healthcare delivery through innovation and technology. The solution aligns with the Universal Immunisation Programme (UIP) by ensuring last-mile temperature integrity for life-saving vaccines, especially in rural and tribal areas. Its IoT-enabled features support the Ayushman Bharat Digital Mission, enhancing transparency and traceability in public health logistics. Furthermore, the device contributes to the objectives of the National Solar Mission through its solar-powered compatibility, reducing dependence on unreliable power sources. Emvólio’s success is also a direct outcome of support under Startup India and reflects India’s growing emphasis on tech-enabled self-reliance in public health infrastructure, a cornerstone of the country’s development goals for 2047.

Proven Results Across States and Borders

Since its inception, Emvólio has delivered over 200,000 vaccines across 16 Indian states and is now being deployed in Africa. The device’s effectiveness is underscored by its WHO PQS prequalification and certification by Indian health authorities. Emvólio has received numerous accolades, including the Best Product against COVID-19 (2022) and the National Startup Award (2023), highlighting its impact and innovation. The device’s ability to maintain a consistent temperature range and reduce vaccine wastage by up to 99% has optimized human resources and extended the cold chain duration, making it a game-changer in vaccine logistics.


From Lab to Field: Challenges and Learnings

Developing Emvólio was not without challenges. The team had to overcome the inherent inefficiencies of thermodynamics and refrigeration processes while ensuring cost-effectiveness. Additionally, changing user mindsets and convincing stakeholders to adopt this new technology required significant effort. However, the success of Emvólio in reducing vaccine wastage and improving delivery efficiency has paved the way for further technological enhancements. The integration of IoT features for continuous monitoring and traceability is set to enhance its functionality and address issues related to counterfeiting and adverse reactions.

Leading the Way in Health-Tech Innovation

Emvólio represents a significant advancement in India’s healthcare technology landscape. By addressing the critical issue of vaccine wastage and enhancing delivery efficiency, it supports the nation’s health infrastructure and aligns with strategic national goals. As Emvólio continues to expand its reach and incorporate advanced features, it holds the potential to transform vaccine logistics not only in India but globally, making it a pivotal player in the quest for a healthier, more self-reliant India.

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