Emvólio: Revolutionizing Vaccine Cold Chain Management for India's Health Sector
In the face of significant vaccine wastage in India, Blackfrog Technologies, a Manipal-based startup, has developed Emvólio, a portable, battery-powered refrigeration unit. This innovation ensures vaccines are maintained at optimal temperatures, drastically reducing wastage and enhancing vaccine delivery efficiency. Emvólio has expanded its impact across 16 Indian states and into Africa.
Updated on: 19 June 2025
Sector
Solution
Technology
State of Origin
Impact Metrics
99% reduction
in vaccine wastage.
2-8°C
maintained for 12-20 hours.
Last-mile vaccine delivery
across 16 Indian states.
Vaccine wastage has long been a critical issue in India, with estimates indicating that 25% of vaccines are lost annually due to inadequate cold chain management. The COVID-19 pandemic highlighted this challenge, with some states reporting wastage rates as high as 37%. The root cause lies in the reliance on traditional iceboxes, which fail to maintain the necessary temperature range of 2℃ to 8℃, leading to spoilage and inefficacy of vaccines. This inefficiency not only wastes resources but also hampers the country’s immunization efforts, particularly in remote areas.
A Portable Breakthrough With Precision Cooling

Blackfrog Technologies, founded by Mayur Shetty in Manipal, Karnataka, has introduced Emvólio, a groundbreaking solution to this problem. Emvólio is a portable refrigeration unit that maintains vaccines at the required temperatures for up to 12 hours, with the potential to extend up to 20 hours. The device incorporates a patented rapid cooling technology, utilizing a Proportional Integral Derivative (PID) controller to ensure precise temperature control. This innovation eliminates the risks associated with traditional methods, such as accidental freezing or thawing, and significantly reduces maintenance costs due to its solid-state cooling mechanism.
Supporting India’s Health and Innovation Missions
Emvólio’s development and deployment reflect India’s broader commitment to strengthening healthcare delivery through innovation and technology. The solution aligns with the Universal Immunisation Programme (UIP) by ensuring last-mile temperature integrity for life-saving vaccines, especially in rural and tribal areas. Its IoT-enabled features support the Ayushman Bharat Digital Mission, enhancing transparency and traceability in public health logistics. Furthermore, the device contributes to the objectives of the National Solar Mission through its solar-powered compatibility, reducing dependence on unreliable power sources. Emvólio’s success is also a direct outcome of support under Startup India and reflects India’s growing emphasis on tech-enabled self-reliance in public health infrastructure, a cornerstone of the country’s development goals for 2047.
Proven Results Across States and Borders
Since its inception, Emvólio has delivered over 200,000 vaccines across 16 Indian states and is now being deployed in Africa. The device’s effectiveness is underscored by its WHO PQS prequalification and certification by Indian health authorities. Emvólio has received numerous accolades, including the Best Product against COVID-19 (2022) and the National Startup Award (2023), highlighting its impact and innovation. The device’s ability to maintain a consistent temperature range and reduce vaccine wastage by up to 99% has optimized human resources and extended the cold chain duration, making it a game-changer in vaccine logistics.

From Lab to Field: Challenges and Learnings
Developing Emvólio was not without challenges. The team had to overcome the inherent inefficiencies of thermodynamics and refrigeration processes while ensuring cost-effectiveness. Additionally, changing user mindsets and convincing stakeholders to adopt this new technology required significant effort. However, the success of Emvólio in reducing vaccine wastage and improving delivery efficiency has paved the way for further technological enhancements. The integration of IoT features for continuous monitoring and traceability is set to enhance its functionality and address issues related to counterfeiting and adverse reactions.
Leading the Way in Health-Tech Innovation
Emvólio represents a significant advancement in India’s healthcare technology landscape. By addressing the critical issue of vaccine wastage and enhancing delivery efficiency, it supports the nation’s health infrastructure and aligns with strategic national goals. As Emvólio continues to expand its reach and incorporate advanced features, it holds the potential to transform vaccine logistics not only in India but globally, making it a pivotal player in the quest for a healthier, more self-reliant India.
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